DDB2 represses ovarian cancer cell dedifferentiation by suppressing ALDH1A1

Cancer stem cells (CSCs), representing the root of many solid tumors including ovarian cancer, have been implicated in disease recurrence, metastasis, and therapeutic resistance. Our previous study has demonstrated that the CSC subpopulation in ovarian cancer can be limited by DNA damage-binding pro...

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Udgivet i:Cell Death Dis
Main Authors: Cui, Tiantian, Srivastava, Amit Kumar, Han, Chunhua, Wu, Dayong, Wani, Nissar, Liu, Lu, Gao, Zhiqin, Qu, Meihua, Zou, Ning, Zhang, Xiaoli, Yi, Ping, Yu, Jianhua, Bell, Erica H., Yang, Shyh-Ming, Maloney, David J., Zheng, Yanfang, Wani, Altaf A., Wang, Qi-En
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948213/
https://ncbi.nlm.nih.gov/pubmed/29752431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0585-y
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