DDB2 represses ovarian cancer cell dedifferentiation by suppressing ALDH1A1

Cancer stem cells (CSCs), representing the root of many solid tumors including ovarian cancer, have been implicated in disease recurrence, metastasis, and therapeutic resistance. Our previous study has demonstrated that the CSC subpopulation in ovarian cancer can be limited by DNA damage-binding pro...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Cui, Tiantian, Srivastava, Amit Kumar, Han, Chunhua, Wu, Dayong, Wani, Nissar, Liu, Lu, Gao, Zhiqin, Qu, Meihua, Zou, Ning, Zhang, Xiaoli, Yi, Ping, Yu, Jianhua, Bell, Erica H., Yang, Shyh-Ming, Maloney, David J., Zheng, Yanfang, Wani, Altaf A., Wang, Qi-En
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948213/
https://ncbi.nlm.nih.gov/pubmed/29752431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0585-y
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