Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4(+) T Cells Permissive for Latent HIV-1 Infection

The latent reservoir for HIV-1 in resting memory CD4(+) T cells is the major barrier to curing HIV-1 infection. Studies of HIV-1 latency have focused on regulation of viral gene expression in cells in which latent infection is established. However, it remains unclear how infection initially becomes...

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Dettagli Bibliografici
Pubblicato in:Immunity
Autori principali: Shan, Liang, Deng, Kai, Gao, Hongbo, Xing, Sifei, Capoferri, Adam A., Durand, Christine M., Rabi, S. Alireza, Laird, Gregory M., Kim, Michelle, Hosmane, Nina N., Yang, Hung-Chih, Zhang, Hao, Margolick, Joseph B., Li, Linghua, Cai, Weiping, Ke, Ruian, Flavell, Richard A., Siliciano, Janet D., Siliciano, Robert F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948104/
https://ncbi.nlm.nih.gov/pubmed/29045905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.09.014
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