Targeting HIV latency: pharmacologic strategies toward eradication

Por Xing, Sifei, Siliciano, Robert F.
Publicado em 2012

Unique characteristics of histone deacetylase inhibitors in reactivation of latent HIV-1 in Bcl-2-transduced primary resting CD4+ T cells

Por Shan, Liang, Xing, Sifei, Yang, Hung-Chih, Zhang, Hao, Margolick, Joseph B., Siliciano, Robert F.
Publicado em 2014

A Critical Subset Model Provides a Conceptual Basis for the High Antiviral Activity of Major HIV Drugs()

Por Shen, Lin, Rabi, S. Alireza, Sedaghat, Ahmad R., Shan, Liang, Lai, Jun, Xing, Sifei, Siliciano, Robert F.
Publicado em 2011

Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation

Por Xing, Sifei, Bhat, Shridhar, Shroff, Neeta S., Zhang, Hao, Lopez, Joseph A., Margolick, Joseph B., Liu, Jun O., Siliciano, Robert F.
Publicado em 2012

Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation

Por Yang, Hung-Chih, Xing, Sifei, Shan, Liang, O’Connell, Karen, Dinoso, Jason, Shen, Anding, Zhou, Yan, Shrum, Cynthia K., Han, Yefei, Liu, Jun O., Zhang, Hao, Margolick, Joseph B., Siliciano, Robert F.
Publicado em 2009

Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4(+) T Cell Model without Inducing Global T Cell Activation

Por Xing, Sifei, Bullen, Cynthia K., Shroff, Neeta S., Shan, Liang, Yang, Hung-Chih, Manucci, Jordyn L., Bhat, Shridhar, Zhang, Hao, Margolick, Joseph B., Quinn, Thomas C., Margolis, David M., Siliciano, Janet D., Siliciano, Robert F.
Publicado em 2011

BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism

Por Boehm, Daniela, Calvanese, Vincenzo, Dar, Roy D., Xing, Sifei, Schroeder, Sebastian, Martins, Laura, Aull, Katherine, Li, Pao-Chen, Planelles, Vicente, Bradner, James E., Zhou, Ming-Ming, Siliciano, Robert F., Weinberger, Leor, Verdin, Eric, Ott, Melanie
Publicado em 2013

The Anti-Hepatitis B Drug Entecavir Inhibits HIV-1 Replication and Can Select HIV-1 Variants Resistant to Antiretroviral Drugs

Por McMahon, Moira A., Jilek, Benjamin L., Brennan, Timothy P., Shen, Lin, Zhou, Yan, Wind-Rotolo, Megan, Xing, Sifei, Bhat, Shridhar, Hale, Braden, Hegarty, Robert, Chong, Curtis R., Liu, Jun O., Siliciano, Robert F., Thio, Chloe L.
Publicado em 2007

An In-Depth Comparison of Latent HIV-1 Reactivation in Multiple Cell Model Systems and Resting CD4+ T Cells from Aviremic Patients

Por Spina, Celsa A., Anderson, Jenny, Archin, Nancie M., Bosque, Alberto, Chan, Jonathan, Famiglietti, Marylinda, Greene, Warner C., Kashuba, Angela, Lewin, Sharon R., Margolis, David M., Mau, Matthew, Ruelas, Debbie, Saleh, Suha, Shirakawa, Kotaro, Siliciano, Robert F., Singhania, Akul, Soto, Paula C., Terry, Valeri H., Verdin, Eric, Woelk, Christopher, Wooden, Stacey, Xing, Sifei, Planelles, Vicente
Publicado em 2013