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A Critical Subset Model Provides a Conceptual Basis for the High Antiviral Activity of Major HIV Drugs()

Control of HIV-1 replication was first achieved with regimens that included a nonnucleoside reverse transcriptase inhibitor (NNRTI) or a protease inhibitor (PI); however, an explanation for the high antiviral activity of these drugs has been lacking. Indeed, conventional pharmacodynamic measures lik...

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Detalhes bibliográficos
Main Authors: Shen, Lin, Rabi, S. Alireza, Sedaghat, Ahmad R., Shan, Liang, Lai, Jun, Xing, Sifei, Siliciano, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488347/
https://ncbi.nlm.nih.gov/pubmed/21753122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002304
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