Reciprocal signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression

Glioblastoma is the most lethal primary brain tumor, however the crosstalk between glioblastoma stem cells (GSCs) and their supportive niche is not well understood. Here, we interrogated reciprocal signaling between GSCs and their differentiated glioblastoma cell (DGC) progeny. We found that DGCs ac...

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Détails bibliographiques
Publié dans:Cell Stem Cell
Auteurs principaux: Wang, Xiuxing, Prager, Briana C., Wu, Qiulian, Kim, Leo J. Y., Gimple, Ryan C., Shi, Yu, Yang, Kailin, Morton, Andrew, Zhou, Wenchao, Zhu, Zhe, Obara, Elisabeth Anne Adanma, Miller, Tyler E., Song, Anne, Lai, Sisi, Hubert, Christopher G., Jin, Xun, Huang, Zhi, Fang, Xiaoguang, Dixit, Deobrat, Tao, Weiwei, Zhai, Kui, Chen, Cong, Dong, Zhen, Zhang, Guoxin, Dombrowski, Stephen M., Hamerlik, Petra, Mack, Stephen C., Bao, Shideng, Rich, Jeremy N.
Format: Artigo
Langue:Inglês
Publié: 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947947/
https://ncbi.nlm.nih.gov/pubmed/29625067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.03.011
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