Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli

BACKGROUND: Fibroblast apoptosis is a critical component of normal repair and the acquisition of an apoptosis-resistant phenotype contributes to the pathogenesis of fibrotic repair. Fibroblasts from fibrotic lungs of humans and mice demonstrate resistance to apoptosis induced by Fas-ligand and prior...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Dodi, Amos E., Ajayi, Iyabode O., Chang, Christine, Beard, Meghan, Ashley, Shanna L., Huang, Steven K., Thannickal, Victor J., Tschumperlin, Daniel J., Sisson, Thomas H., Horowitz, Jeffrey C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946418/
https://ncbi.nlm.nih.gov/pubmed/29747634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0801-4
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