Matrix-driven Myosin II Mediates the Pro-fibrotic Fibroblast Phenotype

Pro-fibrotic mesenchymal cells are known to be the key effector cells of fibroproliferative disease, but the specific matrix signals and the induced cellular responses that drive the fibrogenic phenotype remain to be elucidated. The key mediators of the fibroblast fibrogenic phenotype were character...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Southern, Brian D., Grove, Lisa M., Rahaman, Shaik O., Abraham, Susamma, Scheraga, Rachel G., Niese, Kathryn A., Sun, Huanxing, Herzog, Erica L., Liu, Fei, Tschumperlin, Daniel J., Egelhoff, Thomas T., Rosenfeld, Steven S., Olman, Mitchell A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Glycobiology and Extracellular Matrices
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813589/
https://ncbi.nlm.nih.gov/pubmed/26763235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.712380
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