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Prion protein is essential for the RE1 silencing transcription factor (REST)-dependent developmental switch in synaptic NMDA receptors

It is important that the correct amounts of GluN2 subunits are maintained, as they determine NMDAR functional properties, which are crucial to neuronal communication, synaptogenesis and cognitive function. The transcriptional repressor RE1 silencing transcription factor (REST) is critical for the po...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Song, Zhiqi, Yang, Wei, Cheng, Guangyu, Zhou, Xiangmei, Yang, Lifeng, Zhao, Deming
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945644/
https://ncbi.nlm.nih.gov/pubmed/29748616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0576-z
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