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Novel Repression of Kcc2 Transcription by REST–RE-1 Controls Developmental Switch in Neuronal Chloride
Transcriptional upregulation of Kcc2b, the gene variant encoding the major isoform of the KCC2 chloride transporter, underlies a rapid perinatal decrease in intraneuronal chloride concentration (chloride shift), which is necessary for GABA to act inhibitory. Here we identify a novel repressor elemen...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2833346/ https://ncbi.nlm.nih.gov/pubmed/19923298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2934-09.2009 |
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