Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models

Prion diseases are a group of infectious diseases characterized by multiple neuropathological changes, yet the mechanisms that preserve function and protect against prion-associated neurodegeneration are still unclear. We previously reported that the repressor element 1-silencing transcription facto...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Song, Zhiqi, Shah, Syed Z. A., Yang, Wei, Dong, Haodi, Yang, Lifeng, Zhou, Xiangmei, Zhao, Deming
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413570/
https://ncbi.nlm.nih.gov/pubmed/28515679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00128
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