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REST-dependent epigenetic remodeling promotes the in vivo developmental switch in NMDA receptors

N-methyl-D-aspartate receptors (NMDARs) are critical to synaptogenesis, neural circuitry and higher cognitive functions such as learning and memory. A hallmark feature of NMDARs is an early postnatal developmental switch from primarily GluN2B- to GluN2A-containing. Although the switch in phenotype h...

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Detalhes bibliográficos
Main Authors: Rodenas-Ruano, Alma, Chávez, Andrés E., Cossio, Maria J., Castillo, Pablo E., Zukin, R. Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501125/
https://ncbi.nlm.nih.gov/pubmed/22960932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3214
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