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Gene-by-environment interactions that disrupt mitochondrial homeostasis cause neurodegeneration in C. elegans Parkinson’s models

Parkinson’s disease (PD) is a complex multifactorial disorder where environmental factors interact with genetic susceptibility. Accumulating evidence suggests that mitochondria have a central role in the progression of neurodegeneration in sporadic and/or genetic forms of PD. We previously reported...

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Udgivet i:Cell Death Dis
Main Authors: Kim, Hanna, Perentis, Rylee J., Caldwell, Guy A., Caldwell, Kim A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945629/
https://ncbi.nlm.nih.gov/pubmed/29748634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0619-5
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