Dysregulation of the Mitochondrial Unfolded Protein Response Induces Non-Apoptotic Dopaminergic Neurodegeneration in C. elegans Models of Parkinson's Disease

Due to environmental insult or innate genetic deficiency, protein folding environments of the mitochondrial matrix are prone to dysregulation, prompting the activation of a specific organellar stress-response mechanism, the mitochondrial unfolded protein response (UPR(MT)). In Caenorhabditis elegans...

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Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Martinez, Bryan A., Petersen, Daniel A., Gaeta, Anthony L., Stanley, Samuel P., Caldwell, Guy A., Caldwell, Kim A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2017
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Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688521/
https://ncbi.nlm.nih.gov/pubmed/29030433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1294-17.2017
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