Dysregulation of the Mitochondrial Unfolded Protein Response Induces Non-Apoptotic Dopaminergic Neurodegeneration in C. elegans Models of Parkinson's Disease

Due to environmental insult or innate genetic deficiency, protein folding environments of the mitochondrial matrix are prone to dysregulation, prompting the activation of a specific organellar stress-response mechanism, the mitochondrial unfolded protein response (UPR(MT)). In Caenorhabditis elegans...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Martinez, Bryan A., Petersen, Daniel A., Gaeta, Anthony L., Stanley, Samuel P., Caldwell, Guy A., Caldwell, Kim A.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2017
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688521/
https://ncbi.nlm.nih.gov/pubmed/29030433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1294-17.2017
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