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Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice

Disrupted brain iron homeostasis is a common feature of neurodegenerative disease. To begin to understand how neuronal iron handling might be involved, we focused on dopaminergic neurons and asked how inactivation of transport proteins affected iron homeostasis in vivo in mice. Loss of the cellular...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Matak, Pavle, Matak, Andrija, Moustafa, Sarah, Aryal, Dipendra K., Benner, Eric J., Wetsel, William, Andrews, Nancy C.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822577/
https://ncbi.nlm.nih.gov/pubmed/26929359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519473113
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