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Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice
Disrupted brain iron homeostasis is a common feature of neurodegenerative disease. To begin to understand how neuronal iron handling might be involved, we focused on dopaminergic neurons and asked how inactivation of transport proteins affected iron homeostasis in vivo in mice. Loss of the cellular...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4822577/ https://ncbi.nlm.nih.gov/pubmed/26929359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519473113 |
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