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Alcohol Upregulation of CYP2A5: Role of Reactive Oxygen Species

Hepatic cytochrome P450 (CYP) 2E1 and CYP2A5 activate many important drugs and hepatotoxins. CYP2E1 is induced by alcohol, but whether CYP2A5 is upregulated by alcohol is not known. This article reviews recent studies on the induction of CYP2A5 by alcohol and the mechanism and role of reactive oxyge...

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Dettagli Bibliografici
Pubblicato in:React Oxyg Species (Apex)
Autori principali: Lu, Yongke, Cederbaum, Arthur I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944604/
https://ncbi.nlm.nih.gov/pubmed/29756048
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