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Ethanol Induction of CYP2A5: Role of CYP2E1-ROS-Nrf2 Pathway

Chronic ethanol consumption was previously shown to induce CYP2A5 in mice, and this induction of CYP2A5 by ethanol was CYP2E1 dependent. In this study, the mechanisms of CYP2E1-dependent ethanol induction of CYP2A5 were investigated. CYP2E1 was induced by chronic ethanol consumption to the same degr...

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Bibliografske podrobnosti
Main Authors: Lu, Yongke, Zhang, Xu Hannah, Cederbaum, Arthur I.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493190/
https://ncbi.nlm.nih.gov/pubmed/22552773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs164
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