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Distinct chronology of neuronal cell cycle re-entry and tau pathology in the 3×Tg-AD mouse model and Alzheimer disease patients

Cell cycle re-entry in Alzheimer’s disease (AD) has emerged as an important pathological mechanism in the progression of the disease. This appearance of cell cycle related proteins has been linked to tau pathology in AD, but the causal and temporal relationship between the two is not completely clea...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Hradek, Alex C., Lee, Hyun-Pil, Siedlak, Sandra L., Torres, Sandy L., Jung, Wooyoung, Han, Ashley H., Lee, Hyoung-gon
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944600/
https://ncbi.nlm.nih.gov/pubmed/25061053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-141083
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