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BRCA1 May Modulate Neuronal Cell Cycle Re-Entry in Alzheimer Disease

In Alzheimer disease, neuronal degeneration and the presence of neurofibrillary tangles correlate with the severity of cognitive decline. Neurofibrillary tangles contain the antigenic profile of many cell cycle markers, reflecting a re-entry into the cell cycle by affected neurons. However, while su...

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Detalhes bibliográficos
Main Authors: Evans, Teresa A., Raina, Arun K., Delacourte, André, Aprelikova, Olga, Lee, Hyoung-gon, Zhu, Xiongwei, Perry, George, Smith, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868658/
https://ncbi.nlm.nih.gov/pubmed/17505559
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