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Triple action Pt(iv) derivatives of cisplatin: a new class of potent anticancer agents that overcome resistance
A series of triple action Pt(iv) prodrugs was designed to test the hypothesis that multi-action compounds, where each bioactive moiety intervenes in several cellular processes, might be more effective than a single agent at killing cancer cells. In particular, “triple action” Pt(iv) derivatives of c...
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| Publicado en: | Chem Sci |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5944384/ https://ncbi.nlm.nih.gov/pubmed/29780561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc00428e |
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