Oxidative Stress Induced by Pt(IV) Pro-drugs Based on the Cisplatin Scaffold and Indole Carboxylic Acids in Axial Position

The use of Pt(IV) complexes as pro-drugs that are activated by intracellular reduction is a widely investigated approach to overcome the limitations of Pt(II) anticancer agents. A series of ten mono- and bis-carboxylated Pt(IV) complexes with axial indole-3-acetic acid (IAA) and indole-3-propionic a...

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Vydáno v:Sci Rep
Hlavní autoři: Tolan, Dina, Gandin, Valentina, Morrison, Liam, El-Nahas, Ahmed, Marzano, Cristina, Montagner, Diego, Erxleben, Andrea
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941645/
https://ncbi.nlm.nih.gov/pubmed/27404565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29367
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