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An evolution-based strategy for engineering allosteric regulation

Allosteric regulation provides a way to control protein activity at the time scale of milliseconds to seconds inside the cell. An ability to engineer synthetic allosteric systems would be of practical utility for the development of novel biosensors, creation of synthetic cell signaling pathways, and...

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Bibliographic Details
Published in:Phys Biol
Main Authors: Pincus, David, Resnekov, Orna, Reynolds, Kimberly A.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943710/
https://ncbi.nlm.nih.gov/pubmed/28266924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/aa64a4
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