Human Cortex Spheroid with a Functional Blood Brain Barrier for High-Throughput Neurotoxicity Screening and Disease Modeling

The integral selectivity characteristic of the blood brain barrier (BBB) limits therapeutic options for many neurologic diseases and disorders. Currently, very little is known about the mechanisms that govern the dynamic nature of the BBB. Recent reports have focused on the development and applicati...

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Vydáno v:Sci Rep
Hlavní autoři: Nzou, Goodwell, Wicks, R. T., Wicks, E. E., Seale, S. A., Sane, C. H., Chen, A., Murphy, S. V., Jackson, J. D., Atala, A. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943588/
https://ncbi.nlm.nih.gov/pubmed/29743549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25603-5
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