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SCDT-02. BLOOD-BRAIN-BARRIER SPHEROIDS AS AN IN VITRO SCREENING PLATFORM FOR BRAIN-PENETRATING AGENTS
The inability of most systemically delivered therapeutics to cross the blood-brain-barrier (BBB) is considered a major barrier to effective brain cancer treatment. In malignant glioma the tumor neovasculature is known to be leaky, however invasive cells remain protected behind an intact BBB, and con...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692762/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1086 |
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