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Blood-brain-barrier organoids for investigating the permeability of CNS therapeutics
In vitro models of the blood brain barrier (BBB) are crucial tools for the study of BBB transport and development of drugs that can reach the CNS. Brain endothelial cells grown in culture are often used to model the BBB however it is challenging to maintain reproducible BBB properties and function....
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| Publicado no: | Nat Protoc |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6673652/ https://ncbi.nlm.nih.gov/pubmed/30382243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-018-0066-x |
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