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Colon Cancer-Upregulated Long Non-Coding RNA lincDUSP Regulates Cell Cycle Genes and Potentiates Resistance to Apoptosis

Long non-coding RNAs (lncRNAs) are frequently dysregulated in many human cancers. We sought to identify candidate oncogenic lncRNAs in human colon tumors by utilizing RNA sequencing data from 22 colon tumors and 22 adjacent normal colon samples from The Cancer Genome Atlas (TCGA). The analysis led t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Forrest, Megan E., Saiakhova, Alina, Beard, Lydia, Buchner, David A., Scacheri, Peter C., LaFramboise, Thomas, Markowitz, Sanford, Khalil, Ahmad M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943353/
https://ncbi.nlm.nih.gov/pubmed/29743621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25530-5
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