Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer

Approximately, 25–30% of early-stage breast tumors are classified at the molecular level as HER2-positive, which is an aggressive subtype of breast cancer. Amplification of the HER2 gene in these tumors results in a substantial increase in HER2 mRNA levels, and consequently, HER2 protein levels. HER...

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Vydáno v:Oncotarget
Hlavní autoři: Merry, Callie R., McMahon, Sarah, Forrest, Megan E., Bartels, Cynthia F., Saiakhova, Alina, Bartel, Courtney A., Scacheri, Peter C., Thompson, Cheryl L., Jackson, Mark W., Harris, Lyndsay N., Khalil, Ahmad M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288181/
https://ncbi.nlm.nih.gov/pubmed/27449296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10637
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