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Conserved Function of lincRNAs in Vertebrate Embryonic Development Despite Rapid Sequence Evolution

Thousands of long intervening non-coding RNAs (lincRNAs) have been identified in mammals. To better understand the evolution and functions of these enigmatic RNAs, we used chromatin marks, poly(A)-site mapping and RNA-Seq data, to identify more than 550 distinct lincRNAs in zebrafish. Although these...

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Hlavní autoři: Ulitsky, Igor, Shkumatava, Alena, Jan, Calvin H., Sive, Hazel, Bartel, David P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376356/
https://ncbi.nlm.nih.gov/pubmed/22196729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.11.055
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