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The Non-coding RNA, miR-126, Suppresses the Growth of Neoplastic Cells by Targeting Phosphatidylinositol 3-Kinase Signaling and is Frequently Lost in Colon Cancers
MicroRNAs (miRNA/miR) are a class of small non-coding RNAs implicated in the pathogenesis of various malignancies. In the current study, using micro(RNA)arrays, we found a ubiquitous loss of miR-126 expression in colon cancer lines when compared to normal human colon epithelia. Reconstitution of miR...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739997/ https://ncbi.nlm.nih.gov/pubmed/18663744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20596 |
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