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The Non-coding RNA, miR-126, Suppresses the Growth of Neoplastic Cells by Targeting Phosphatidylinositol 3-Kinase Signaling and is Frequently Lost in Colon Cancers

MicroRNAs (miRNA/miR) are a class of small non-coding RNAs implicated in the pathogenesis of various malignancies. In the current study, using micro(RNA)arrays, we found a ubiquitous loss of miR-126 expression in colon cancer lines when compared to normal human colon epithelia. Reconstitution of miR...

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Bibliografiset tiedot
Päätekijät: Guo, Chunguang, Sah, Frank J., Beard, Lydia, Willson, James K. V., Markowitz, Sanford D., Guda, Kishore
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739997/
https://ncbi.nlm.nih.gov/pubmed/18663744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20596
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