ロード中...
RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly
Intracellular membrane trafficking is essential for eukaryotic cell existence. Here, we show that RAB37 activation through GTP binding recruits ATG5-12 to isolation membrane and promotes autophagosome formation through the ATG5-ATG12-ATG16L1 complex. RAB37 is localized on the isolation membrane. It...
保存先:
| 出版年: | Cell Death Differ |
|---|---|
| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2017
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5943352/ https://ncbi.nlm.nih.gov/pubmed/29229996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0023-1 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|