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A Mammalian Autophagosome Maturation Mechanism Mediated by TECPR1 and The Atg12-Atg5 Conjugate

Autophagy is a major catabolic pathway in eukaryotes associated with a broad spectrum of human diseases. In autophagy, autophagosomes carrying cellular cargoes fuse with lysosomes for degradation. However, the molecular mechanism underlying autophagosome maturation is largely unknown. Here we report...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Chen, Dandan, Fan, Weiliang, Lu, Yiting, Ding, Xiaojun, Chen, She, Zhong, Qing
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299828/
https://ncbi.nlm.nih.gov/pubmed/22342342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.12.036
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