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A Mammalian Autophagosome Maturation Mechanism Mediated by TECPR1 and The Atg12-Atg5 Conjugate
Autophagy is a major catabolic pathway in eukaryotes associated with a broad spectrum of human diseases. In autophagy, autophagosomes carrying cellular cargoes fuse with lysosomes for degradation. However, the molecular mechanism underlying autophagosome maturation is largely unknown. Here we report...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3299828/ https://ncbi.nlm.nih.gov/pubmed/22342342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.12.036 |
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