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A Mammalian Autophagosome Maturation Mechanism Mediated by TECPR1 and The Atg12-Atg5 Conjugate
Autophagy is a major catabolic pathway in eukaryotes associated with a broad spectrum of human diseases. In autophagy, autophagosomes carrying cellular cargoes fuse with lysosomes for degradation. However, the molecular mechanism underlying autophagosome maturation is largely unknown. Here we report...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3299828/ https://ncbi.nlm.nih.gov/pubmed/22342342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.12.036 |
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