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Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L)
The class III phosphatidylinositol 3-kinase (PI3KC3) is crucial for autophagosome biogenesis. It has been long speculated to nucleate the autophagosome membrane, but the biochemical mechanism of such nucleation activity remains unsolved. We recently identified Barkor/Atg14(L) as the targeting factor...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093500/ https://ncbi.nlm.nih.gov/pubmed/21518905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016472108 |
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