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Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L)

The class III phosphatidylinositol 3-kinase (PI3KC3) is crucial for autophagosome biogenesis. It has been long speculated to nucleate the autophagosome membrane, but the biochemical mechanism of such nucleation activity remains unsolved. We recently identified Barkor/Atg14(L) as the targeting factor...

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Bibliografske podrobnosti
Main Authors: Fan, Weiliang, Nassiri, Ashley, Zhong, Qing
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093500/
https://ncbi.nlm.nih.gov/pubmed/21518905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016472108
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