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Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L)

The class III phosphatidylinositol 3-kinase (PI3KC3) is crucial for autophagosome biogenesis. It has been long speculated to nucleate the autophagosome membrane, but the biochemical mechanism of such nucleation activity remains unsolved. We recently identified Barkor/Atg14(L) as the targeting factor...

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Detalhes bibliográficos
Main Authors: Fan, Weiliang, Nassiri, Ashley, Zhong, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093500/
https://ncbi.nlm.nih.gov/pubmed/21518905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016472108
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