Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation

p53 is a transcription factor that is implicated in the control of both apoptotic and autophagic cell death. This tumor suppressor elicits both pro-autophagic and anti-autophagic phenotypes depending of its intracellular localization. The ability of p53 to repress autophagy has been exclusively asso...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Differ
Prif Awduron: Goiran, Thomas, Duplan, Eric, Rouland, Lila, el Manaa, Wejdane, Lauritzen, Inger, Dunys, Julie, You, Han, Checler, Frédéric, Alves da Costa, Cristine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943347/
https://ncbi.nlm.nih.gov/pubmed/29352272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0016-0
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