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The Transcription Factor Function of Parkin: Breaking the Dogma

PRKN (PARK2) is a key gene involved in both familial and sporadic Parkinson’s disease that encodes parkin (PK). Since its discovery by the end of the 90s, both functional and more recently, structural studies led to a consensual view of PK as an E3 ligase only. It is generally considered that this f...

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Detalles Bibliográficos
Publicado en:Front Neurosci
Main Authors: Alves da Costa, Cristine, Duplan, Eric, Rouland, Lila, Checler, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341214/
https://ncbi.nlm.nih.gov/pubmed/30697141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00965
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