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The Transcription Factor Function of Parkin: Breaking the Dogma

PRKN (PARK2) is a key gene involved in both familial and sporadic Parkinson’s disease that encodes parkin (PK). Since its discovery by the end of the 90s, both functional and more recently, structural studies led to a consensual view of PK as an E3 ligase only. It is generally considered that this f...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Neurosci
Egile Nagusiak: Alves da Costa, Cristine, Duplan, Eric, Rouland, Lila, Checler, Frédéric
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341214/
https://ncbi.nlm.nih.gov/pubmed/30697141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00965
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