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miRNA-21 ablation protects against liver injury and necroptosis in cholestasis
Inhibition of microRNA-21 (miR-21) prevents necroptosis in the mouse pancreas. Necroptosis contributes to hepatic necro-inflammation in the common bile duct ligation (BDL) murine model. We aimed to evaluate the role of miR-21 in mediating deleterious processes associated with cholestasis. Mechanisti...
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| Publicado no: | Cell Death Differ |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5943330/ https://ncbi.nlm.nih.gov/pubmed/29229992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0019-x |
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