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miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice

microRNAs were recently suggested to contribute to the pathogenesis of nonalcoholic fatty liver disease (NAFLD), a disease lacking specific pharmacological treatments. In that regard, nuclear receptors are arising as key molecular targets for the treatment of nonalcoholic steatohepatitis (NASH). Her...

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Detalles Bibliográficos
Publicado en:Cell Death Dis
Main Authors: Rodrigues, Pedro M, Afonso, Marta B, Simão, André L, Carvalho, Catarina C, Trindade, Alexandre, Duarte, António, Borralho, Pedro M, Machado, Mariana V, Cortez-Pinto, Helena, Rodrigues, Cecília MP, Castro, Rui E
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477590/
https://ncbi.nlm.nih.gov/pubmed/28406477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.172
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