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Bioluminescence imaging enhances analysis of drug responses in a patient-derived xenograft model of pediatric ALL

PURPOSE: Robust preclinical models of pediatric acute lymphoblastic leukemia (ALL) are essential in prioritizing promising therapies for clinical assessment in high-risk patients. Patient-derived xenograft (PDX) models of ALL provide a clinically relevant platform for assessing novel drugs, with eff...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Jones, Luke, Richmond, Jennifer, Evans, Kathryn, Carol, Hernan, Jing, Duohui, Kurmasheva, Raushan T., Billups, Catherine A., Houghton, Peter J., Smith, Malcolm A., Lock, Richard B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943062/
https://ncbi.nlm.nih.gov/pubmed/28119366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2392
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