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Increased hydrophobic surface exposure in the cataract-related G18V variant of human γS-crystallin
BACKGROUND: The objective of this study was to determine whether the cataract-related G18V variant of human γS-crystallin has increased exposure of hydrophobic residues that could explain its aggregation propensity and/or recognition by αB-crystallin. METHODS: We used an ANS fluorescence assay and N...
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| Publicado no: | Biochim Biophys Acta |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5942885/ https://ncbi.nlm.nih.gov/pubmed/26459004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2015.09.022 |
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