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How are growth hormone and insulin-like growth factor-1 reported as markers for drug effectiveness in clinical acromegaly research? A comprehensive methodologic review

OBJECTIVE: In rare disease research, most randomized prospective clinical trials can only use limited number of patients and are comprised of highly heterogeneous populations. Therefore, it is crucial to report the results in such a manner that it allows for comparison of treatment effectiveness and...

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Détails bibliographiques
Publié dans:Pituitary
Auteurs principaux: van Esdonk, Michiel J., van Zutphen, Eline J. M., Roelfsema, Ferdinand, Pereira, Alberto M., van der Graaf, Piet H., Biermasz, Nienke R., Stevens, Jasper, Burggraaf, Jacobus
Format: Artigo
Langue:Inglês
Publié: Springer US 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942341/
https://ncbi.nlm.nih.gov/pubmed/29605877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11102-018-0884-4
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