Synthetic glycan-based TLR4 agonists targeting caspase-4/11 for the development of adjuvants and immunotherapeutics

Gram-negative bacterial lipopolysaccharide (LPS)-induced Toll-like receptor 4 (TLR4) mediated pro-inflammatory signaling plays a key role in immunoprotection against infectious challenges and boosts adaptive immunity, whereas the activation of the cytosolic LPS receptor caspase-4/11 leads to cell de...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Chem Sci
Auteurs principaux: Adanitsch, Florian, Shi, Jianjin, Shao, Feng, Beyaert, Rudi, Heine, Holger, Zamyatina, Alla
Format: Artigo
Langue:Inglês
Publié: Royal Society of Chemistry 2018
Sujets:
Chemistry
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941199/
https://ncbi.nlm.nih.gov/pubmed/29780528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc05323a
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires