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The ‘allosteron’ model for entropic allostery of self-assembly

Using the simple ‘allosteron’ model, we show that it is possible, in principle, to elicit pathways by which fluctuation allostery affects self-assembly of protein complexes. We treat the cases of (i) protein fibrils and nucleation, (ii) n-mer protein complexes, and (iii) weakly attractive allosteric...

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Detalhes bibliográficos
Publicado no:Philos Trans R Soc Lond B Biol Sci
Main Authors: McLeish, Tom, Schaefer, C., von der Heydt, A. C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941180/
https://ncbi.nlm.nih.gov/pubmed/29735739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2017.0186
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