Global low-frequency motions in protein allostery: CAP as a model system

Allostery is a fundamental process by which ligand binding to a protein alters its activity at a distant site. There is considerable evidence that allosteric cooperativity can be communicated by the modulation of protein dynamics without conformational change. The Catabolite Activator Protein (CAP)...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biophys Rev
Main Authors: Townsend, Philip D., Rodgers, Thomas L., Pohl, Ehmke, Wilson, Mark R., McLeish, Tom C. B., Cann, Martin J.
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2015
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432019/
https://ncbi.nlm.nih.gov/pubmed/26000062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-015-0163-9
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