Genetic alterations analysis in prognostic stratified groups identified TP53 and ARID1A as poor clinical performance markers in intrahepatic cholangiocarcinoma

The incidence and mortality rates of intrahepatic cholangiocarcinoma have been rising worldwide. Few patients present an early-stage disease that is amenable to curative surgery and after resection, high recurrence rates persist. To identify new independent marker related to aggressive behaviour, tw...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Simbolo, Michele, Vicentini, Caterina, Ruzzenente, Andrea, Brunelli, Matteo, Conci, Simone, Fassan, Matteo, Mafficini, Andrea, Rusev, Borislav, Corbo, Vincenzo, Capelli, Paola, Bria, Emilio, Pedron, Serena, Turri, Giona, Lawlor, Rita T., Tortora, Giampaolo, Bassi, Claudio, Guglielmi, Alfredo, Scarpa, Aldo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940669/
https://ncbi.nlm.nih.gov/pubmed/29740198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25669-1
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