Genetic alterations analysis in prognostic stratified groups identified TP53 and ARID1A as poor clinical performance markers in intrahepatic cholangiocarcinoma

The incidence and mortality rates of intrahepatic cholangiocarcinoma have been rising worldwide. Few patients present an early-stage disease that is amenable to curative surgery and after resection, high recurrence rates persist. To identify new independent marker related to aggressive behaviour, tw...

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izdano v:Sci Rep
Main Authors: Simbolo, Michele, Vicentini, Caterina, Ruzzenente, Andrea, Brunelli, Matteo, Conci, Simone, Fassan, Matteo, Mafficini, Andrea, Rusev, Borislav, Corbo, Vincenzo, Capelli, Paola, Bria, Emilio, Pedron, Serena, Turri, Giona, Lawlor, Rita T., Tortora, Giampaolo, Bassi, Claudio, Guglielmi, Alfredo, Scarpa, Aldo
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940669/
https://ncbi.nlm.nih.gov/pubmed/29740198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25669-1
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