Multigene mutational profiling of cholangiocarcinomas identifies actionable molecular subgroups

One-hundred-fifty-three biliary cancers, including 70 intrahepatic cholangiocarcinomas (ICC), 57 extrahepatic cholangiocarcinomas (ECC) and 26 gallbladder carcinomas (GBC) were assessed for mutations in 56 genes using multigene next-generation sequencing. Expression of EGFR and mTOR pathway genes wa...

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Detalhes bibliográficos
Main Authors: Simbolo, Michele, Fassan, Matteo, Ruzzenente, Andrea, Mafficini, Andrea, Wood, Laura D., Corbo, Vincenzo, Melisi, Davide, Malleo, Giuseppe, Vicentini, Caterina, Malpeli, Giorgio, Antonello, Davide, Sperandio, Nicola, Capelli, Paola, Tomezzoli, Anna, Iacono, Calogero, Lawlor, Rita T., Bassi, Claudio, Hruban, Ralph H., Guglielmi, Alfredo, Tortora, Giampaolo, de Braud, Filippo, Scarpa, Aldo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058049/
https://ncbi.nlm.nih.gov/pubmed/24867389
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