20(S)-protopanaxadiol regio-selectively targets androgen receptor: anticancer effects in castration-resistant prostate tumors

We have explored the effects of 20(S)-protopanaxadiol (aPPD), a naturally derived ginsenoside, against androgen receptor (AR) positive castration resistant prostate cancer (CRPC) xenograft tumors and have examined its interactions with AR. In silico docking studies for aPPD binding to AR, alongside...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Ben-Eltriki, Mohamed, Deb, Subrata, Hassona, Mohamed, Meckling, Gray, Fazli, Ladan, Chin, Mei Yieng, Lallous, Nada, Yamazaki, Takeshi, Jia, William, Rennie, Paul S., Cherkasov, Artem, Tomlinson Guns, Emma S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940378/
https://ncbi.nlm.nih.gov/pubmed/29765513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24695
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