20(S)-protopanaxadiol regio-selectively targets androgen receptor: anticancer effects in castration-resistant prostate tumors

We have explored the effects of 20(S)-protopanaxadiol (aPPD), a naturally derived ginsenoside, against androgen receptor (AR) positive castration resistant prostate cancer (CRPC) xenograft tumors and have examined its interactions with AR. In silico docking studies for aPPD binding to AR, alongside...

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發表在:Oncotarget
Main Authors: Ben-Eltriki, Mohamed, Deb, Subrata, Hassona, Mohamed, Meckling, Gray, Fazli, Ladan, Chin, Mei Yieng, Lallous, Nada, Yamazaki, Takeshi, Jia, William, Rennie, Paul S., Cherkasov, Artem, Tomlinson Guns, Emma S.
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2018
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940378/
https://ncbi.nlm.nih.gov/pubmed/29765513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24695
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