20(S)-protopanaxadiol regio-selectively targets androgen receptor: anticancer effects in castration-resistant prostate tumors

We have explored the effects of 20(S)-protopanaxadiol (aPPD), a naturally derived ginsenoside, against androgen receptor (AR) positive castration resistant prostate cancer (CRPC) xenograft tumors and have examined its interactions with AR. In silico docking studies for aPPD binding to AR, alongside...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Ben-Eltriki, Mohamed, Deb, Subrata, Hassona, Mohamed, Meckling, Gray, Fazli, Ladan, Chin, Mei Yieng, Lallous, Nada, Yamazaki, Takeshi, Jia, William, Rennie, Paul S., Cherkasov, Artem, Tomlinson Guns, Emma S.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940378/
https://ncbi.nlm.nih.gov/pubmed/29765513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24695
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